DIABETES-MELLITUS

Citation
H. Andersen et J. Jakobsen, DIABETES-MELLITUS, Current opinion in neurology, 10(5), 1997, pp. 376-380
Citations number
21
Categorie Soggetti
Neurosciences,"Clinical Neurology
ISSN journal
13507540
Volume
10
Issue
5
Year of publication
1997
Pages
376 - 380
Database
ISI
SICI code
1350-7540(1997)10:5<376:D>2.0.ZU;2-R
Abstract
Epidemiological studies have documented a high prevalence of diabetic neuropathy. The risk of lower leg amputation is increased three to fou r times in patients with clinical signs of neuropathy and ankle weakne ss is more common than hitherto recognized. Increased nerve hydration and increased expression of low affinity p75 receptor for neurotrophin s suggest new therapeutic potentials for the prevention of diabetic ne uropathy.