SARCOIDOSIS IN A CHILD WITH SICKLE-CELL-ANEMIA

Purpose: The purpose of this case report is to (a) present a detailed description of a child with sickle cell anemia who developed sarcoidos is, (b) compare the clinical aspects of sickle cell anemia and sarcoid osis, and (c) review the literature with respect to the coincidence of these two diseases. Detailed clinical case history and laboratory fin dings are presented. A literature review of other case reports with ch ildren and adults who have both sickle cell anemia and sarcoidosis is given. Results: Based on limited data, there may be an increased incid ence of sarcoidosis in adults with sickle cell diseases. No data are a vailable in the pediatric population. Conclusions: Sarcoidosis is diff icult to diagnose in children with sickle cell anemia. The clinical ma nifestations of sickle cell anemia and sarcoidosis have overlapping fe atures but represent distinct syndromes. Patients with sickle cell ane mia who have unusual signs and symptoms need to be further evaluated f or the possibility of other coincident diseases, including sarcoidosis .