ENZYMATIC RESOLUTION OF (+ -)-TRANS-2-AMINOCYCLOHEXAUOL AND (+/-)-TRANS-2-AMINOCYCLOPENTANOL/

Authors
MAESTRO A ASTORGA C GOTOR V
Citation
A. Maestro et al., ENZYMATIC RESOLUTION OF (+ -)-TRANS-2-AMINOCYCLOHEXAUOL AND (+/-)-TRANS-2-AMINOCYCLOPENTANOL/, Tetrahedron : asymmetry, 8(18), 1997, pp. 3153-3159
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
18
Year of publication
1997
Pages
3153 - 3159
Database
ISI
SICI code
0957-4166(1997)8:18<3153:ERO(-A>2.0.ZU;2-A
Abstract
Candida antarctica lipase (GAL) catalyzes the resolution of (+/-)-tran s-2-aminocyclohexanol by alkoxycarbonylation or acylation reactions. B esides, N-benzyloxycarbonyl derivatives of (+/-)-trans-2-aminocyclohex anol and (+/-)-trans-2-aminocyclopentanol are efficiently resolved thr ough O-acylation by Pseudomonas cepacia lipase (PSL). (C) 1997 Elsevie r Science Ltd.