NEUROSONOGRAPHIC DIAGNOSIS OF THALAMIC BASAL GANGLIA VASCULOPATHY IN TRISOMY-13 - AN IMPORTANT DIAGNOSTIC-AID/

We performed a retrospective review of all the infants diagnosed with trisomy 13 in our institution from 1982 to 1995 and evaluated the neur osonographic findings along with their clinical information and cytoge netic analysis, Nine babies were admitted with trisomy 13. Sonography of the head was performed on 4 patients, and demonstrated in all of th em a linear, branching, echogenic pattern in the thalamus/basal gangli a, Doppler evaluation of the thalamus/basal ganglia was performed in 3 of the 4 cases and confirmed these linear echogenicities to be of vas cular origin, This is the first study to evaluated the occurrence of t his finding in a specific syndrome, namely trisomy 13. (C) 1997 Wiley- Liss, Inc.