Systemic donor infection is regarded as being an absolute contraindica
tion to cadaveric organ donation for transplantation. This is largely
due to fear of transmitting pathogenic organisms to the immunosuppress
ed recipient. However, due to the current shortage of organs available
for transplantation, clinicians are faced with the option of using or
gans from 'non-ideal' donors, such as those patients with documented e
vidence of infection. We report the successful outcome of six orthotop
ic liver transplants, 11 renal transplants, one combined heart lung tr
ansplant and one simultaneous kidney and pancreas transplant with orga
ns from eight donors in whom bacterial meningitis (n=7) and acute bact
erial epiglottitis (n=1) were the antecedent causes of death.