Background Q fever is a world-wide condition caused by the rickettsia
Coxiella burnetii. It appears more prevalent in agrarian communities a
nd may have serious sequelae. Methods A descriptive, cross-sectional,
observational study using a randomly selected group of the adult worki
ng practice population in a rural practice in West Wales was devised.
An immunofluorescence test, which identified past infection, was used
to look for associations between C. burnetii seropositivity and farm-r
elated or social activities, and to compare the findings with those of
other studies. An attempt was made to establish a clinical profile fo
r the illness Q fever. Results Twenty-one subjects were found to be se
ropositive to C. burnetii. No definite consistent clinical features we
re identified. Farming was undoubtedly a risk factor for the disease,
maybe with other related factors also important. There was a possibili
ty that alcohol had a protective effect. No sinister sequelae were des
cribed. Conclusions Q fever occurs more frequently in farmers than in
non-farmers, but was less common than previously thought. Is Q fever a
ccurately described in medical textbooks? A case is made for a more co
-operative approach between primary carers and epidemiologists in the
study of illnesses in populations.