Background: Human cysticercosis is secondary to an infestation by cyst
icercus cellulosae, the larval form of Taenia solium. Cysticercosis is
endemic to regions with poor sanitation. The purpose of this report i
s to present a large series of patients with orbital cysticercosis and
to discuss the current treatment. Methods: A retrospective chart anal
ysis of all patients with orbital cysticercosis from an urban practice
in southern India was performed. The clinical features, the results o
f investigations, the therapies instituted, and the outcomes realized
were recorded. Results: Twenty patients diagnosed with orbital cystice
rcosis were identified (11 female and 9 male). Their ages ranged from
5 to 25 years with a mean age of 12.5 years. Nine patients manifested
subconjunctival cysts. Eight were excised and 5 of these were densely
adherent to the adjacent extraocular muscle (EOM). The remaining 11 pa
tients had a cyst in a single EOM. The EOM cysts had proptosis, restri
cted motility, recurrent inflammation, and blepharoptosis. Two of the
EOM cysts were excised surgically and four extruded spontaneously. Six
patients with EOM cysts were treated medically: they all received ora
l corticosteroids and, additionally, five were given oral albendazole
and one was given oral praziquantel. Conclusions: Excisional biopsy is
recommended for subconjunctival cysticercosis. Idiopathic cystic myos
itis can present like EOM cysticercosis, but is differentiated by reso
lution with corticosteroid treatment. Medical therapy in orbital cysti
cercosis with oral albendazole and corticosteroids can arrest recurren
t inflammation and improve ocular motility.