Vascular complications of thoracic outlet syndrome are uncommon but ma
y result in significant long-term disability. This report documents a
retrospective review of 17 such patients. Ten patients presented with
acute onset of upper extremity swelling and axillosubclavian vein thro
mbosis. One patient presented with chronic, intermittent arm swelling
and subclavian vein stenosis. Three patients presented with acute symp
toms of upper extremity emboli, and three presented with chronic arm c
laudication. Cervical ribs were discovered in four patients with arter
ial symptoms and in no patients with venous symptoms. All ten patients
with acute venous thrombosis underwent successful thrombolysis, with
venous stenosis uncovered in 8. Thrombolysis was also performed for tw
o patients with arterial emboli. All 17 patients underwent surgical de
compression of the thoracic outlet, 16 via a supraclavicular approach
and one via a transaxillary approach. One subclavian arteriotomy with
endarterectomy and one resection of a subclavian artery aneurysm were
performed at the time of decompression. Repeat venography after decomp
ression demonstrated persistent venous stenosis in one patient that wa
s treated with balloon angioplasty and stenting. After a mean of 22 mo
nths' follow-up, 12 patients had no residual symptoms, and 5 had exper
ienced significant improvement of symptoms. In conclusion, a combined
approach of thrombolysis and surgical decompression of the thoracic ou
tlet provides a salutary outcome in a majority of patients.