The case of a 76-year-old diabetic patient with known aortic valve scl
erosis is reported. One week after implantation of a permanent pacemak
er system (indication: 2nd degree AV-block type Mobitz) he developed f
ever. Large endocarditic vegetations were found on the aortic and mitr
al valve (blood cultures: were positive for Staphylococcus aureus). Al
so from the pacemaker bed Staphylococcus aureus was isolated and an an
tibiotic treatment including vancomycin was started. Nevertheless the
patient developed insufficiencies of both the aortic and mitral valves
and became hemodynamically unstable. Due to cerebral embolisms and fu
rther deterioration of the patient's overall clinical state the alread
y planned operative replacement of the aortic and mitral valve could n
ot be performed. The patient died because of left ventricular failure
after pacemaker infection which was complicated by endocarditis.