PANENCEPHALOPATHIC TYPE OF CREUTZFELDT-JAKOB-DISEASE ASSOCIATED WITH CADAVERIC DURA-MATER GRAFT

Citation
M. Yamada et al., PANENCEPHALOPATHIC TYPE OF CREUTZFELDT-JAKOB-DISEASE ASSOCIATED WITH CADAVERIC DURA-MATER GRAFT, Journal of Neurology, Neurosurgery and Psychiatry, 63(4), 1997, pp. 524-527
Citations number
13
Categorie Soggetti
Psychiatry,"Clinical Neurology
ISSN journal
00223050
Volume
63
Issue
4
Year of publication
1997
Pages
524 - 527
Database
ISI
SICI code
0022-3050(1997)63:4<524:PTOCAW>2.0.ZU;2-R
Abstract
A 52 year old man with Creutzfeldt-Jakob disease who received a cadave ric dura mater graft 99 months before the onset is reported. The prion protein gene was homozygous for methionine at the polymorphic codon 1 29. Neuropathological examination disclosed a panencephalopathic type of Creutzfeldt-Jakob disease which was characterised by severe involve ment of the cerebral white matter and cerebellum, as well as of the ce rebral cortical and deep grey matter. Thus the panencephalopathic type of Creutzfeldt-Jakob disease may occur in association with cadaveric dura mater grafts.