DELETION POLYMORPHISM IN THE GENE FOR ANGIOTENSIN-CONVERTING ENZYME IS ASSOCIATED WITH ELEVATED FASTING BLOOD-GLUCOSE LEVELS

Authors
ZINGONE A DOMINIJANNI A MELE E MARASCO O MELINA F MINCHELLA P QUARESIMA B TIANO MT GNASSO A PUJIA A PERROTTI N
Citation
A. Zingone et al., DELETION POLYMORPHISM IN THE GENE FOR ANGIOTENSIN-CONVERTING ENZYME IS ASSOCIATED WITH ELEVATED FASTING BLOOD-GLUCOSE LEVELS, Human genetics, 94(2), 1994, pp. 207-209
Citations number
15
Categorie Soggetti
Genetics & Heredity
Journal title
Human genetics → ACNP
ISSN journal
03406717
Volume
94
Issue
2
Year of publication
1994
Pages
207 - 209
Database
ISI
SICI code
0340-6717(1994)94:2<207:DPITGF>2.0.ZU;2-5
Abstract
The frequency and distribution of angiotensin converting enzyme insert ion/deletion (ACE I/D) polymorphism, and its association with other kn own risk factors for coronary atherosclerosis, has been studied, in a normal south Italian population. Subjects homozygous for deletion show ed elevated fasting blood glucose levels when compared with subjects h omozygous for insertion. The difference was consistent with an increas ed number of type 2 diabetics among the former group of subjects.