Intravascular papillary endothelial hyperplasia (IPEH) is a rare benig
n reactive lesion usually found in thrombosed subcutaneous blood vesse
ls. It uncommonly occurs in the central nervous system and may be mist
aken for a more malignant type of tumour such as angiosarcoma. We pres
ent a first case of multiple IPEH occurring intracranially in a 51-yea
r-old woman. She developed neurological compromises secondary to the m
ass affect of the haematoma arising from one of the lesions. Prompt su
rgical evacuation of the haematoma stabilized her condition. Surgical
treatment, pathological findings, radiographic characteristics, and a
review of the literature are presented.