ANTIINFLAMMATORY ACTIVITY OF (CRESOXYACETATO)COPPER(II) COMPLEXES

Authors
BLAHOVA M SOKOLIK J TUMOVA I SVEC P
Citation
M. Blahova et al., ANTIINFLAMMATORY ACTIVITY OF (CRESOXYACETATO)COPPER(II) COMPLEXES, Chemicke listy, 91(9), 1997, pp. 641-642
Citations number
4
Categorie Soggetti
Chemistry
Journal title
Chemicke listy → ACNP
ISSN journal
00092770
Volume
91
Issue
9
Year of publication
1997
Pages
641 - 642
Database
ISI
SICI code
0009-2770(1997)91:9<641:AAO(C>2.0.ZU;2-O
Abstract
The anti-inflammatory activity of mononuclear aqua(cresoxyacetato)copp er(II)complexes was assayed in rat paw carrageenan edema. The antiphlo gistic effects of the tested complexes were compared to those of the c orresponding acids, salicylic acid and its Cu(II) salt. Cu(II) complex es were more effective than the free acetic acids, with exception for the o-cresoxy derivative. Both m- and p-cresoxyacetate copper(II)-comp lexes exhibited a higher activity (71%) compared to that of copper(II) salicylate tetrahydrate (58%).