N-(4-Phenyl-2-thiazolyl)-2-propenamides IVa-h resulted in the reaction
of N-(4-phenyl-2-thiazolyl)cyanoacetamide (II) with 4-substituted ben
zaldehydes. Compounds IVa-g were cyclized with malonodinitrile in the
presence of piperidine to the corresponding polysubstituted 1-(4-pheny
l-2-thiazolyl)-2-pyridones Va-g.