F. Gregan et al., UTILIZATION OF HOMOLOGICAL SERIES OF SELECTED ORGANIC-COMPOUNDS IN STUDIES OF THEIR PROPERTIES, Chemicke listy, 91(9), 1997, pp. 677-678
Using stereoselective reactions two homological series of diastereisom
eric +/- cis and +/- trans lkoxyphenylcarbymoyloxy]-cycloheptylmethyla
mmonium chlorides containing 1,2,3,4 and 6 carbon atoms in alkyl chain
were prepared. The principal physicochemical characteristics, includi
ng partition coefficients, were determined and relative local anesthet
ic activity was measured.