R. Edwards et D. Greenwood, DISTINCTIVE OUTER-MEMBRANE PROTEIN AND LIPOPOLYSACCHARIDE COMPOSITIONOF BACTEROIDES-FRAGILIS STRAINS THAT PRODUCE METALLO-BETA-LACTAMASE, Anaerobe, 3(4), 1997, pp. 233-236
The outer membrane protein and lipopolysaccharide compositions of Bact
eroides fragilis strains which produced metallo-beta-lactamase were sh
own to be different from those of fully sensitive random clinical isol
ates of Bacteroides fragilis in which metallo-beta-lactamase productio
n was not detected. This may reflect differences in the permeability b
arrier and provides phenotypic evidence that Bacteroides fragilis whic
h produce metallo-beta-lactamase may belong to a separate biotype. Out
er membrane profiles may provide a rapid means of identifying these pr
oblem strains. (C) 1997 Academic Press.