Pvp. Pragnacharyulu et E. Abushanab, STEREOSPECIFIC SYNTHESIS OF 2'-DEOXY PYRIMIDINE AND 5,6-DIHYDRO 5-HYDROXY THYMIDINE NUCLEOSIDES, Tetrahedron letters, 38(40), 1997, pp. 7025-7028
An economic and versatile synthesis of 2'-deoxy and 2',3'-dideoxy pyri
midine nucleosides is described. Readily available oxazoline 1 is cond
ensed with glycidate 2 to give anhydro nucleoside 3. This is converted
to the title compounds following established routes. (C) 1997 Elsevie
r Science Ltd.