J. Kauhanen et al., BEER BINGING AND MORTALITY - RESULTS FROM THE KUOPIO ISCHEMIC-HEART-DISEASE RISK FACTOR STUDY, A PROSPECTIVE POPULATION-BASED STUDY, BMJ. British medical journal, 315(7112), 1997, pp. 846-851
Objective: To examine the association between beer binging (regular se
ssions of heavy beer drinking) and mortality. Design: Prospective popu
lation based study with the baseline assessment of level of alcohol in
take (dose), by type of drink and drinking pattern, previous and exist
ing diseases, socioeconomic background, occupational status, involveme
nt in organisations during leisure time, physical activity in leisure
time, body mass index, blood pressure, serum lipids and plasma fibrino
gen concentration, during an average of 7.7 years' follow up of mortal
ity. Setting: Finland. Subjects: A population sample of 1641 men who c
onsumed beer who were aged 42, 48, 54, or 60 years at baseline. Main o
utcome measures: All cause mortality, cardiovascular mortality, death
due to external causes, fatal myocardial infarctions. Results: The ris
k of death was substantially increased in men whose usual dose of beer
was 6 or more bottles per session compared with men who usually consu
med less than 3 bottles, after adjustment forage and total alcohol con
sumption (relative risk 3.01 (95% confidence interval 1.54 to 5.90) fo
r all deaths; 7.10 (2.01 to 25.12) for external deaths; and 6.50 (2.05
to 20.61) for fatal myocardial infarction). The association changed o
nly slightly when smoking, occupational status, previous diseases, sys
tolic blood pressure, low density lipoprotein and high density lipopro
tein cholesterol concentration, plasma fibrinogen concentration, body
mass index, marital status, leisure time physical activity, and involv
ement in organisations were controlled for. Conclusion: The pattern of
beer binging is associated with increased risk of death, independentl
y of the total average consumption of alcoholic drinks. The relation i
s not explained by known behavioural, psychosocial, or biological risk
factors. Death due to injuries and other external causes is overrepre
sented.