SYNTHESIS OF [H-3(2)]-21-DIAZOPROGESTERONE AS A POTENT PHOTOAFFINITY-LABELING REAGENT FOR THE MINERALOCORTICOID RECEPTOR

Authors
FAGART J SOBRIO F MARQUET A
Citation
J. Fagart et al., SYNTHESIS OF [H-3(2)]-21-DIAZOPROGESTERONE AS A POTENT PHOTOAFFINITY-LABELING REAGENT FOR THE MINERALOCORTICOID RECEPTOR, Journal of labelled compounds & radiopharmaceuticals, 39(10), 1997, pp. 791-795
Citations number
17
Categorie Soggetti
Chemistry Analytical","Pharmacology & Pharmacy","Biochemical Research Methods
Journal title
Journal of labelled compounds & radiopharmaceuticals → ACNP
ISSN journal
03624803
Volume
39
Issue
10
Year of publication
1997
Pages
791 - 795
Database
ISI
SICI code
0362-4803(1997)39:10<791:SO[AAP>2.0.ZU;2-9
Abstract
[H-3(2)]-21-Diazoprogesterone ([H-3]21DP), a potent photoaffinity labe lling reagent, has been synthesized in four steps from progesterone. T ritium has been introduced by homogeneous tritiation with Wilkinson's Catalyst.