TERTIARY-AMINES - A DECISIVE FACTOR IN THE STEREOSELECTIVE ADDITION OF (R)-PANTOLACTONE TO N-PHTHALYL VALINE KETENE

Citation
M. Calmes et al., TERTIARY-AMINES - A DECISIVE FACTOR IN THE STEREOSELECTIVE ADDITION OF (R)-PANTOLACTONE TO N-PHTHALYL VALINE KETENE, Tetrahedron, 53(40), 1997, pp. 13719-13726
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00404020
Volume
53
Issue
40
Year of publication
1997
Pages
13719 - 13726
Database
ISI
SICI code
0040-4020(1997)53:40<13719:T-ADFI>2.0.ZU;2-O
Abstract
The stereoselective base-catalyzed addition of (R)-pantolactone to the ketene derived from racemic N-phthalyl valine is reported. The R or S configuration of the newly generated asymmetric centre of the pantola ctonyl ester is highly dependent on the tertiary amine catalyst employ ed. (C) 1997 Elsevier Science Ltd.