THE WITHDRAWAL TIME-ESTIMATION OF VETERINARY DRUGS - A NONPARAMETRIC APPROACH

Citation
D. Concordet et Pl. Toutain, THE WITHDRAWAL TIME-ESTIMATION OF VETERINARY DRUGS - A NONPARAMETRIC APPROACH, Journal of veterinary pharmacology and therapeutics, 20(5), 1997, pp. 374-379
Citations number
3
Categorie Soggetti
Pharmacology & Pharmacy","Veterinary Sciences
ISSN journal
01407783
Volume
20
Issue
5
Year of publication
1997
Pages
374 - 379
Database
ISI
SICI code
0140-7783(1997)20:5<374:TWTOVD>2.0.ZU;2-H
Abstract
The study of a veterinary drug for use in a food producing animal requ ires the estimation of the withdrawal time which is defined as the tim e when it can be assessed with a controlled risk that a given percenta ge (less than 100(1-alpha)%) of animals have a concentration below the Maximal Limit of Residue (MRL), A simple and understandable non-param etric method which allows the control of the risk is presented, This m ethod does not require the assumptions needed for the correct use of t he current method of estimation to be met, A simple example which illu strates the use of this method is presented.