RADIOLOGICAL FEATURES OF THE VISCERAL AND SKELETAL INVOLVEMENT OF HEMOCHROMATOSIS

Hemochromatosis is a multisystem disorder produced by the excessive ac cumulation of iron in visceral organs and the musculoskeletal system. Clinically the disease may be silent, but characteristic radiological features may point to the diagnosis. The increased iron stores in the organs involved, especially in the liver and pancreas, result in an in creased attenuation at unenhanced CT and an decreased signal intensity at MR imaging. Hemochromatosis arthropathy includes degenerative oste oarthritis and chondrocalcinosis. The distribution of the arthropathy is distinctive, but not unique, frequently affecting the second and th ird metacarpophalangeal joints of the hand.