EFFECTS OF INTRAVENTRICULAR HEMORRHAGE AND HYDROCEPHALUS ON THE LONG-TERM NEUROBEHAVIORAL DEVELOPMENT OF PRETERM VERY-LOW-BIRTH-WEIGHT INFANTS

Measures of intelligence, neuropsychological functions, academic skill s, and behavioral adjustment were obtained at school-age from children born preterm with no hydrocephalus (N=29), arrested hydrocephalus (N= 19), and shunted hydrocephalus (N=17), and a term comparison group (N= 23), Most children also received concurrent neurological examinations and MRI brain scans, Results revealed significantly poorer neurobehavi oral development in all four domains in preterm children with shunted hydrocephalus, Despite abnormal MRI findings in virtually all children with arrested hydrocephalus, significant differences between preterm children with arrested hydrocephalus and those with no hydrocephalus w ere largely in areas involving attentional and academic skills, Preter m children with no hydrocephalus tended to show poorer motor developme nt relative to term children, Neurological abnormalities were restrict ed to children with spasticity in the arrested (N=2) and shunted (N=10 ) groups, These results highlight the importance of separating cases a ccording to residual neurological and neuroimaging abnormalities in ac counting for variations in the neurobehavioral development of preterm, low-birth-weight infants.