MOLECULAR-CLONING AND MAPPING OF A HUMAN CDNA (PA2G4) THAT ENCODES A PROTEIN HIGHLY HOMOLOGOUS TO THE MOUSE-CELL CYCLE PROTEIN P38-2G4

Authors
LAMARTINE J SERI M CINTI R HEITZMANN F CREAVEN M RADOMSKI N JOST E LENOIR GM ROMEO G SYLLA BS
Citation
J. Lamartine et al., MOLECULAR-CLONING AND MAPPING OF A HUMAN CDNA (PA2G4) THAT ENCODES A PROTEIN HIGHLY HOMOLOGOUS TO THE MOUSE-CELL CYCLE PROTEIN P38-2G4, Cytogenetics and cell genetics, 78(1), 1997, pp. 31-35
Citations number
11
Categorie Soggetti
Cell Biology","Genetics & Heredity
Journal title
Cytogenetics and cell genetics → ACNP
ISSN journal
03010171
Volume
78
Issue
1
Year of publication
1997
Pages
31 - 35
Database
ISI
SICI code
0301-0171(1997)78:1<31:MAMOAH>2.0.ZU;2-8
Abstract
We have identified a novel human gene with strong homology to the mous e Pa2g4 cell cycle gene. This novel gene (called PA2G4) belongs to a g ene family with members in several chromosome regions: 3q24-q25, 6q22, 9q21, 12q13, 18q12, 20p12 and Xq25. A composite cDNA of 1697 nucleoti des was isolated. The sequence of this cDNA predicts a protein of 394 amino acids. The deduced amino acid sequence of this human protein sho ws very strong homology to the mouse protein p38-2G4. The cDNA analyze d probably corresponds to a functional copy found at 12q13.