BIOCHEMICAL-STUDIES ON ANTIMICROBIAL EFFECTIVE FLUORO-IMINE LIGANDS AND THEIR ORGANOTIN(IV) DERIVATIVES

Coordination behavior of fluoro-imines having NS and NO donor moieties towards the diorganotin(IV) have been investigated. The unimolar and bimolar reactions of diorgano tin(IV) chlorides with monobasic bidenta te fluoro ligands resulted in the formation of coloured solids, which have been characterized by elemental analysis, molecular weight determ inations and conductance measurements. Structures of the resulting com plexes have been proposed using IR, H-1, C-13 and Sn-119 NMR spectral studies. The pathogenicity and virulence of certain microbial infectio ns associated with ions of complexes have been found to be potent and broad spectrum antibiotics. These results, made it desirable to deline ate a comparison between ligands and their metal complexes.