PARTICULARITY OF INVASIVE PULMONARY ASPER GILLOSIS IN CHRONIC GRANULOMATOUS-DISEASE - ABOUT 2 TUNISIAN CASES

Citation
S. Belhadj et al., PARTICULARITY OF INVASIVE PULMONARY ASPER GILLOSIS IN CHRONIC GRANULOMATOUS-DISEASE - ABOUT 2 TUNISIAN CASES, Journal de mycologie medicale, 7(3), 1997, pp. 166-168
Citations number
11
Categorie Soggetti
Mycology
ISSN journal
11565233
Volume
7
Issue
3
Year of publication
1997
Pages
166 - 168
Database
ISI
SICI code
1156-5233(1997)7:3<166:POIPAG>2.0.ZU;2-N
Abstract
The authors report two Tunisian cases of invasive pulmonary aspergillo sis, one caused by Aspergillus fumigatus, the other by A. nidulans, ob served in two children with chronic granulomatous disease: pathology c haracterized by hereditary abnormality of oxydative response of phagoc ytic cells, frequently complicated by Aspergillus infections. Despite of a long therapy by amphotericin B and 5-fluorocystosine, the course of the disease was rapid and fatal with bone destruction and extension at skin of pulmonary lesions.