CHROMATOGRAPHY ON CHIRAL STATIONARY PHASES

An overview is given of the development of the variety of chiral stati onary phase materials that are available today for the direct separati on of enantiomers by different chromatographic methods. Applications o f these range from trace analytical determinations of enantiomeric com position in biological materials to large scale preparative isolation of enantiopure compounds of industrial importance. These chromatograph ic techniques are also of interest for studies of mechanism and dynami cs, like enantiomerization processes due to chiral inversion taking pl ace in thermally labile chiral molecular structures.