R. Goodman et C. Libanati, MULTIPLE-MYELOMA - DIAGNOSTIC CLUES IN A PATIENT PRESENTING WITH INCAPACITATING ARTHRALGIAS, Postgraduate medicine, 102(4), 1997, pp. 197
Multiple myeloma is characterized by the production of a monoclonal im
munoglobulin, free monoclonal light chains, or both. Although bone pai
n is the classic presentation, multiple myeloma should be a considerat
ion in differential diagnosis in elderly patients with arthritic compl
aints if other typical symptoms or laboratory abnormalities, such as a
nemia, hypercalcemia, and elevated ESR, are present. A combination of
radiation therapy and chemotherapy is the usual treatment.