INTRACYTOPLASMIC SPERM INJECTION IN OBSTRUCTIVE AND NONOBSTRUCTIVE AZOOSPERMIA

We compared the results of intracytoplasmic sperm injection (ICSI) in: (i) obstructive versus non-obstructive azoospermia, (ii) obstructive azoospermia using epididymal versus testicular spermatozoa and (iii) a cquired versus congenital obstructive azoospermia due to congenital ab sence of the vas deferens (CAVD), A retrospective analysis was done of 241 consecutive ICSI cycles done in 103 patients,vith non-obstructive azoospermia and 119 patients with obstructive azoospermia, In the obs tructive group, 135 ICSI cycles were performed. Epididymal spermatozoa were used in 44 cycles and testicular spermatozoa in 91 cycles, In th e non-obstructive group, 106 cycles were performed, The fertilization and pregnancy per cycle rates were 59.5 and 27.3% respectively using e pididymal spermatozoa, 54.4 and 31.9% respectively using testicular sp ermatozoa in obstructive cases, and 39 and 11.3% respectively in non-o bstructive cases. The fertilization and pregnancy per cycle rates were 56.6 and 37% respectively in acquired obstructive cases, and 55.2 and 20.4% respectively in CAVD, In conclusion, ICSI using spermatozoa fro m patients with acquired obstructive azoospermia resulted in significa ntly higher fertilization and pregnancy rates as compared to CAVD and non-obstructive cases.