SENSITIVITY AND SPECIFICITY OF OPTIC DISC VARIABLES AND ANALYSIS OF ANEW VARIABLE (MP D) FOR GLAUCOMA DIAGNOSIS WITH THE GLAUCOMA-SCOPE/

Aim-In an attempt to use the quantitative optic disc measurements of t he Glaucoma-Scope (OIS Sacramento, CA, USA) to distinguish glaucomatou s from normal optic discs, a new variable was investigated, the mean d isc corrected for the-disc size by dividing by the disc area: MP/D. Me thods-Glaucoma-Scope disc evaluation was performed on 81 eyes of 51 pa tients split into the following groups based on Humphrey 24-2 visual f ield and clinical criteria of glaucoma: chronic glaucoma n=27 (includi ng only early, n=17, and low tension glaucoma, n=10), ocular hypertens ion n=24, pseudoglaucomatous large discs, n=12, and normal eyes, n=18. Classic optic disc variables (the vertical and horizontal c/d ratios, and the c/d area) were compared with the new MP/D index calculating r eceiver operating characteristic curves. Results-The MP/D ratio was ab le to identify the glaucomatous eyes more easily than other ratios. Ar eas under the curves were: 0.91 (MP/D); 0.87 (c/d area); 0.85 (c/d ver tical); and 0.80 (c/d horizontal). The MP/D index was also correlated with the mean deviation (r=0.466; p=0.001). Conclusion-MP/D may prove useful in detecting glaucomatous optic nerve damage and could be an in teresting screening tool for primary open angle glaucoma.