PURPOSE: The aims of this study were to assess the results of biofeedb
ack treatment in constipated patients and to identify variables that m
ight be used to predict the outcome. METHOD: Twenty-eight patients (5
men; median age, 46 (range, 22-72) years) with any degree of paradoxic
al activation measured with thin hook needle electromyography in the e
xternal sphincter or puborectalis muscle were included. The symptom du
ration varied between I and 30 (median, 9) years. The patients had eig
ht outpatient training sessions with electromyography-based audiovisua
l feedback. All patients were followed up prospectively with a validat
ed bowel function questionnaire from which a symptom index was created
. RESULTS: At three months, nine patients had no improvement and under
went other treatments. The remaining 19 patients were followed up for
a median of 14 (range, 12-34) months. Twelve patients (43 percent) sta
ted they had improved rectal emptying. A good result was associated wi
th increased stool frequency (P < 0.05), improved symptom index (P < 0
.01), and reduction of laxative use (P < 0.05). A long symptom duratio
n, a high pretreatment symptom index, and laxative use were related to
a poor result (P < 0.01-0.05). The improved group had less perineal d
escent (P < 0.05), and a prominent puborectalis impression on defecogr
aphy tended to be more common (P = 0.06). CONCLUSION: With the use of
wide inclusion criteria, biofeedback was successful in 43 percent of p
atients, with a treatment effect lasting at least one year. The result
s suggest that biofeedback should be used as the initial treatment of
constipated patients with a paradoxical puborectalis contraction.