SERUM IMMUNOGLOBULIN-E (IG-E) LEVELS AFTER MYOCARDIAL-INFARCTION

The relation between cardiovascular diseases and serum immunoglobulin E (Ig E) levels has been investigated by different authors. Serum Ig E may play a direct role in The pathogenesis of cardiovascular diseases , or it may only be a marker formed during pathological mechanisms. In this study, we determined serum Ig E levels of patients with unstable angina pectoris and myocardial infarction. Serum Ig E levels of 30 pa tients with acute myocardial infarction and 20 patients with unstable angina pectoris were deter-mined within the first 6 and 12th hours and on 2nd, 4th, 8th days of the hospitalization and these levels were co mpared with the serum Ig E levels of normal subjects reserved as contr ol group. As a result, at all measurement hours, serum Ig E levels of acute myocardial infraction group were found to be approximately fourf old increased when compared to those of unstable angina pectoris and t hose of control group (p<0.001). In the acute myocardial infarction gr oup, no significant differences could he found between the levels of t he first 6th and 12th hours nod on the 2nd, 4th, 8th days. Also, no st atistically significant difference was found between the serum Ig E le vels of unstable angina pectoris and those of control group.