BIOELECTRIC BRAIN ACTIVITY IN PATIENTS WITH SYNDROME OF FRAGILE X-CHROMOSOME AND IN THEIR MOTHERS

30 patients (4-22 years old) and their 12 mothers were examined by mea ns of method of electroencephalography (EEG). Healhty individuals of c orresponding age were included in the control group. EEG changes of th e same type were observed in all the patients with syndrome of fragile X-chromosome: reduction of occipital alpha-rhythm, prevalence of thet a-rhythm in central-parietal and central frontal regions as well as ep ileptoid activity in parietal and central-parietal cortical regions. T hese peculiarities could be considered as the markers in syndrome's di agnostics. EEG of mothers (heterozygous carriers of mutant gene) were characterised by considerable variations: increase of roland rhythm's presentation in central cortical zones, accumilation of hypersynchrono us EEG, increase of rhythmical theta-activity, etc. EEG of mother with shift-like schizophrenia resembled one of proband in one case.