Am. Joshi et al., POTENCY TESTING OF INACTIVATED TISSUE-CULTURE VACCINE AGAINST JAPANESE ENCEPHALITIS USING ANTIGEN CAPTURE ELISA, Acta virologica, 41(3), 1997, pp. 157-159
The potency of vaccines against Japanese encephalitis (JE) is usually
determined by a mouse challenge test. In the present study, an antigen
capture enzyme-linked immunosorbent assay (ELISA) using monoclonal an
tibodies (MoAbs) was used to screen inactivated tissue culture JE vacc
ine lots. This test is simple, quick and reliable besides being very s
ensitive and specific.