POTENCY TESTING OF INACTIVATED TISSUE-CULTURE VACCINE AGAINST JAPANESE ENCEPHALITIS USING ANTIGEN CAPTURE ELISA

Citation
Am. Joshi et al., POTENCY TESTING OF INACTIVATED TISSUE-CULTURE VACCINE AGAINST JAPANESE ENCEPHALITIS USING ANTIGEN CAPTURE ELISA, Acta virologica, 41(3), 1997, pp. 157-159
Citations number
11
Categorie Soggetti
Virology
Journal title
ISSN journal
0001723X
Volume
41
Issue
3
Year of publication
1997
Pages
157 - 159
Database
ISI
SICI code
0001-723X(1997)41:3<157:PTOITV>2.0.ZU;2-W
Abstract
The potency of vaccines against Japanese encephalitis (JE) is usually determined by a mouse challenge test. In the present study, an antigen capture enzyme-linked immunosorbent assay (ELISA) using monoclonal an tibodies (MoAbs) was used to screen inactivated tissue culture JE vacc ine lots. This test is simple, quick and reliable besides being very s ensitive and specific.