COMPARISON OF THE MODELS DESCRIBING THE RETENTION IN MICELLAR LIQUID-CHROMATOGRAPHY WITH HYBRID ELUENTS FOR A GROUP OF BENZENE-DERIVATIVES AND POLYCYCLIC AROMATIC-HYDROCARBONS

Some models for predicting capacity factors of benzene derivatives and some polycyclic aromatic hydrocarbons as a function of surfactant and organic modifier concentrations in micellar liquid chromatography wit h hybrid eluents have been tested. The surfactants used in this study were hexadecyltrimethylammonium bromide and sodium dodecyl, sulphate a nd as organic modifiers n-propanol and n-butanol were employed both on C-8 and C-18 columns. The equation that best explains the experimenta l results is 1/k' = A mu + B phi(2) + C phi + D mu phi + E so we propo se the use of this model in conjunction with the appropriate factorial design to predict the solute retention behaviour in micellar liquid c hromatography with hybrid eluents.