Minimally invasive cardiac surgery has generated a tremendous amount o
f enthusiasm in the cardiology and cardiac surgical communities. Coron
ary revascularization without cardiopulmonary bypass through a small a
nterior thoracotomy or mediastinotomy has been introduced as an altern
ative to the conventional approach. An endovascular or port-access tec
hnique for cardiopulmonary bypass and cardioplegic arrest has been dev
eloped for use in cardiac surgery. This peripherally based system achi
eves aortic occlusion, cardioplegia delivery, and left ventricular dec
ompression; thus, coronary revascularization and various cardiac proce
dures can be effectively performed in a less invasive fashion than con
ventional median sternotomy. Continued technical advances in minimally
invasive cardiac surgery will facilitate these procedures, increase p
atient safety, and contribute to acceptable long-term results.