POTENT ANTIINFLAMMATORY 3-THIAZOLE-4(5)-ACETIC ACIDS OF 1,2-BENZISOTHIAZOLE

Authors
SHARMA PK SAWHNEY SN
Citation
Pk. Sharma et Sn. Sawhney, POTENT ANTIINFLAMMATORY 3-THIAZOLE-4(5)-ACETIC ACIDS OF 1,2-BENZISOTHIAZOLE, Bioorganic & medicinal chemistry letters, 7(18), 1997, pp. 2427-2430
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
18
Year of publication
1997
Pages
2427 - 2430
Database
ISI
SICI code
0960-894X(1997)7:18<2427:PA3AO1>2.0.ZU;2-H
Abstract
A number of 1,2-benzisothiazole derivatives, having 2-thiazolyl-4(5)-a cetic acid moiety attached to position-3 of 1,2-benzisothiazole nucleu s, were prepared and evaluated as antiinflammatory agents. Some of the se were found to possess excellent level of antiinflammatory activity in carrageenin-induced rat paw edema assay. (C) 1997 Elsevier Science Ltd.