Based upon the literature, we discuss epidemiological, histopathologic
al, clinical and treatment aspects of postirradiation sarcomas. The ri
sk of postirradiation sarcoma is very low and negligible in comparison
with the beneficial effect of radiotherapy, and it should not be a ma
jor factor influencing treatment decision in patients with cancer. The
radical surgical approach of postirradiation sarcoma is the treatment
which offers the best chance for cure.