THE PROPER CHOICE OF AN ANTIINFECTIOUS IN PETS

The rational choice of an antiinfectious in pet animals is based on a quadruple analysis: clinical, bacteriological, pharmacological and tox icological. This brief review insists on the second and third chapters . In bacteriology, a totally rationalized method using antibiogram is often, economically speaking, difficult to achieve: still, it is possi ble to recommand a semi-empirical (or probabilist) method based on an epidemiological knowledge of the aetiology of infections. In pharmacol ogy, the knowledge of the mode of action of the antiinfectious and its pharmacokinetics are both very important for the final choice.