5 EPISODES OF TRANSIENT APLASTIC-ANEMIA IN 3 PATIENTS

We report five episodes of severe aplastic anemia (AA) followed by spo ntaneous remission in three patients. They were classified as transien t aplastic anemia (TAA). Two were females and one male of 32, 56 and 4 1 years of age, respectively; the man had two recurrences. They had be en in contact with insecticides, solvents or drug ingestion. The three had fever, anemia and muco-cutaneous purpura. Supportive measures wer e used (transfusion of packed red blood cells and platelets, antibioti cs, corticosteroids and danazol, the latter two given for ten days in three episodes). They showed spontaneous remission after 16 to 45 days of evolution. The patients did not suffer infection or myeloprolifera tive disorders which might explain the AA. Transient AA is infrequent and should be considered a variant of AA.