S. Kobayashi et al., CHOROSELECTIVE ENZYMATIC POLYMERIZATION FOR SYNTHESIS OF NATURAL POLYSACCHARIDES, Journal of macromolecular science. Pure and applied chemistry, A34(10), 1997, pp. 2135-2142
By employing an enzymatic polymerization of activated glycosyl monomer
s like glycosyl fluorides and a sugar oxazoline derivative, natural po
lysaccharides like cellulose, xylan, and chitin, have successfully bee
n synthesized. Regio and stereochemistry of these reactions was perfec
tly controlled by the action of enzyme catalysts. Further study on the
synthetic cellulose formation brought about a new concept ''chorosele
ctivity'' concerning a spacial (three dimensional) direction control i
n ordering of macromolecular chains during the polymerization.