A RESEARCH AGENDA FOR AIDS-PREVENTION IN THE DEVELOPING-WORLD

Background: In the developing world, HIV is spreading in many epidemio logic patterns, ranging from slow spread in limited segments of the po pulation to exponential growth to mature epidemics. These differences are superimposed on widely varying cultures and patterns of behavior, creating unique challenges for prevention in each setting. Local preve ntion research is continually necessary to respond appropriately and e ffectively to local prevention needs and to best use scarce resources. The research agenda: We propose a research agenda for AIDS prevention in the developing world, consisting of three main components: epidemi ologic and behavioral surveillance; enhancing local understanding of H IV risk behavior; and testing interventions. We review examples of eac h. This 'bottom-up' research is contrasted with 'top-down' research co nducted in the developing world by scientists from developed countries to answer questions of general interest. Results: The articles publis hed in this volume exemplify the scope and importance of AIDS preventi on research in the developing world. They also show what can be accomp lished through international collaboration directed towards meeting lo cal needs.