R. Brancato et al., MYCOBACTERIUM-CHELONAE KERATITIS AFTER EXCIMER-LASER PHOTOREFRACTIVE KERATECTOMY, Archives of ophthalmology, 115(10), 1997, pp. 1316-1318
This is the first report of a severe case of Mycobacterium chelonae ke
ratitis; ii occurred in a 26-year-old man after he had undergone excim
er laser photorefractive keratectomy for the correction of severe myop
ia, once the epithelium was already healed. The diagnosis was made by
culture results and acid-fast staining of corneal scrapings. Topical c
iprofloxacin sodium, 0.3 mg/mL, plus amikacin sodium, 10 mg/mL, and or
al clarithromycin sodium led to, remission of the ulceration after 3 m
onths of therapy. Subsequent topical corticosteroid therapy led to com
plete visual recovery during 1 year of follow-up. There may be an incr
eased risk of severe keratitis during the first postoperative months i
n eyes that have already undergone photorefractive keratectomy, due to
the presence of some microepithelial defects symptomatically negative
and not easily detectable by slit-lamp examination.