A patient presented with chest pain, fever, and chills and developed a
large pleural effusion while receiving antibiotic therapy, On a CT sc
an of the chest, multiple loculi of fluid were noted, and at surgery,
a complex empyema with an associated bronchopleural fistula related to
a granulomatous process in the lower lobe of the light lung was demon
strated, Cultures revealed Histoplasma capsulatum in the pleural fluid
as well as in the pulmonary parenchymal process.