PREPARATION OF 2-(2-CYANOETHYL)SULFANYL-1H-ISOINDOLE AND RELATED SULFUR-TRANSFER AGENTS

Authors
KLOSE J REESE CB SONG QL
Citation
J. Klose et al., PREPARATION OF 2-(2-CYANOETHYL)SULFANYL-1H-ISOINDOLE AND RELATED SULFUR-TRANSFER AGENTS, Tetrahedron, 53(42), 1997, pp. 14411-14416
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
42
Year of publication
1997
Pages
14411 - 14416
Database
ISI
SICI code
0040-4020(1997)53:42<14411:PO2ARS>2.0.ZU;2-8
Abstract
The title compound 3 and 4-[(2-cyanoethyl)sulfanyl]morpholine-3,5-dion e 12 are both conveniently prepared in good yield from 2-cyanoethyl di sulfide. which itself is readily prepared in one step from S-(2-cyanoe thyl)isothiouronium chloride 4. In the same way, dimethyl and diphenyl disulfides are convened into 2-methylsulfanyl- and 2-phenylsulfanyl-1 H-isoindole 1,3-(2H)-diones 8a and 8b, respectively, also in good yiel ds. (C) 1997 Elsevier Science Ltd.