Jr. Obrien et Nm. George, SENSITIVITY OF AEROBIC SPORE-FORMING SPECIES OF THE GENUS BACILLUS TOTHE PTERIDINE COMPOUND O129, Microbios, 90(363), 1997, pp. 71-78
Discs containing the pteridine compound O129 at various concentrations
may be useful in differentiating the following closely related specie
s belonging to the genus Bacillus, viz. B. subtilis, B. licheniformis
and B. pumilus; B. polymyxa and B. macerans; together with B. cereus a
nd its subspecies B. cereus var. mycoides. At concentrations of 10 mu
g O129, the ATCC type strain of B. subtilis was resistant whereas B, l
icheniformis and B. pumilus were sensitive. However, B, subtilis was s
ensitive to O129 at 150 mu g. Similar reactions differentiated the ATC
C type strains of B. polymyxa and B. macerans. The ATCC type strain of
B. cereus was resistant to O129 at both 150 mu g and 10 mu g, but its
subspecies B. cereus var. mycoides (ATCC 28) was partially sensitive
at 150 mu g concentration. When clinical isolates of B. cereus var. my
coides were subsequently tested, this partial sensitivity was found to
be a variable characteristic.