OSTEOBLAST RESPONSES TO BMP-2-TREATED TITANIUM IN-VITRO

In this study, the phenotypic expression of osteoblast progenitor cell s, 2T9, on characterized titanium surfaces was examined in the presenc e of a bone morphogenetic protein-2 (BMP-2). X-ray photoelectron spect roscopy spectra indicated the presence of titanium dioxide on titanium surfaces, along with surface contaminants such as carbon and nitrogen . In the in vitro study, the activity of BMP-e-treated osteoblast cell s on titanium surfaces was marked by significantly higher alkaline pho sphatase-specific activity and 1,25 (OH2) vitamin D-3-stimulated osteo calcin production when compared to the untreated cells on titanium sur faces.