AUTOIMMUNE IDIOPATHIC THROMBOCYTOPENIC PURPURA WITH THE SUBSEQUENT OCCURRENCE OF SYSTEMIC LUPUS-ERYTHEMATOSUS

Cutaneous manifestations of petechiae, purpura, and ecchymosis can lea d the physician to discover an underlying platelet abnormality, Autoim mune idiopathic thrombocytopenic purpura (AITP) is a diagnosis of excl usion, mediated by a destructive IgG antibody response to the platelet s' membrane components, In addition to showing evidence of cutaneous a nd mucosal bleeding tie, epistaxis, hematuria), patients with AITP are at an increased risk for systemic lupus erythematosus (SLE), Therefor e, it is suggested that patients with AITP be closely monitored for SL E.