CONGENITAL SYNDROMES ASSOCIATED WITH NONMELANOMA SKIN-CANCER

Syndromes associated with nonmelanoma skin cancer are part of a group of inherited disorders characterized by a wide variety of clinical man ifestations including palmar and plantar pitting, calcification of the dura, jaw cysts, and skeletal abnormalities. The syndromes have in co mmon skin lesions progressing to basal or squamous cell cancers. In ad dition to skin tumors, bone and visceral tumors are common. Early diag nosis, genetic counseling, and treatment of skin lesions are appropria te tools for the management of patients with these syndromes. Surgical procedures generally involve total resection combined with reconstruc tive efforts.