EXTRAGENITAL MALIGNANT MIXED MULLERIAN TUMOR

Reports of extragenital malignant mixed Mullerian tumor (MMMT) type th ough extremely rare have increased. This represents the 15th reported case of MMMT outside the female reproductive tract. A 68-year-old blac k woman presenting with abdominal pain, increasing abdominal girth, an d a provisional diagnosis of ovarian carcinoma, underwent exploratory laparotomy, total abdominal hysterectomy, omentectomy and cytoreductiv e surgery. Surgery and histology revealed MMMT of heterologous type in the pelvic peritoneum, with no tumor in the genitalia and no foci of endometriosis. Despite surgical debulking leaving residual tumor of le ss than 1 cm followed by aggressive systemic chemotherapy, the patient died of disease within 2 months. Increasing exploratory surgery may a ccount for the increase in reports of extragenital MMMT. Aggressive tu mor debulking and multiagent systemic chemotherapy is of limited effic acy since extragenital MMMT, like uterine MMMT with pelvic spread, has short survival.